RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-22
RNA ID
MI0000570
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
Scratch wound assay; PCR etc.
Target
MIMECAN
Pathway
NA
PubMed ID
22538858
Title
MicroRNA-22 increases senescence and activates cardiac fibroblasts in the aging heart
Year
2013
Function
miR-22 upregulation in the aging heart contributed at least partly to accelerated cardiac fibroblast senescence and increased migratory activity.